A total of two to seven implants (average, four) were delivered under general or local anesthesia. Ninety-six percent of patients reported immediate symptom relief with significantly improved mean Qmax, PVR, IPSS, and QoL (p<.001) within the first month, which either remained unchanged or improved for up to 18 months. Sexual function including ejaculation was unchanged or even improved in those who reported sexual activity prior to surgery. Adverse events were negligible. Three patients (4%) had unsatisfactory results and subsequently underwent repeat PUL (one patient) with positive results, or TURP (two patients).
Lift holds advantages for old, young patients
“Further advantages of PUL include shorter surgery time, no intra-surgery bleeding, and an outpatient option (depending on the medical system). This new treatment is likely to be a particularly attractive option for young patients who do not want to face retrograde ejaculation or old patients with comorbidities who take anticoagulants and need to avoid major surgery that can induce bleeding,” Dr. Sievert said.
Dr. Sievert explained that the study’s patient follow-up was unique because candidates were not excluded based on oral therapy for lower urinary tract symptoms, high PVR, PV, or history of urinary retention.
“The only exclusion criteria were an obstructive median lobe or high entrance into the bladder,” Dr. Sievert said.
“You cannot expect the flow or residual to be as good as when you remove tissue, but according to the IPSS score, patients value their QoL significantly and were very satisfied. The BPH-6 study that compares the UroLift system to TURP takes a better look at flow and residual and will be reported soon,” he added.
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