Complication type affects decision
On multivariate logistic regression analysis, experiencing a complication was found to reduce the odds that a man would pursue active surveillance, with an odds ratio (OR) of 0.83 (p=.049).
“When we broke it down further by type of complication, it was the noninfectious complication that seems to account for this finding,” Dr. Adamsky said. The OR of pursuing active surveillance after a noninfectious complication was 0.82 (p=.0472) compared with 0.93 (p=.7406) after an infectious complication.
The group’s hypothesis was that men who experienced a complication “are likely risk averse, they’re more anxious, although the other side of this is that it may be physician-driven,” she said. “A physician may at that point counsel them that active treatment is more appropriate because they themselves want to avoid this headache, although there is evidence that we know that having one complication after biopsy does not increase your risk of complications after subsequent biopsies.”
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