Boston—Results of a retrospective case-cohort study show no significant differences in surgical outcomes among men who did and did not have preoperative magnetic resonance imaging (MRI) of the prostate prior to radical prostatectomy for prostate cancer.
Commentary - Prostate MRI: Value in surgical planning?
The research, which was presented at the AUA annual meeting in Boston by urologists from Washington University School of Medicine, St. Louis, included 192 men who received prostate MRI within 6 months of prostatectomy. They were identified from 589 men who underwent prostatectomy for prostate cancer between January 2012 and June 2016 and then matched 1:1 using propensity scoring analysis based on age, Charlson Comorbidity Index, PSA, body mass index, and biopsy Gleason score with men operated on without preoperative prostate MRI.
Surgical outcomes analyzed were operative time, estimated blood loss, perioperative complications, lymph node yield, and positive surgical margin rate. There was a trend for a higher complication rate in patients who had preoperative MRI compared with those who did not (24.0% vs. 16.7%; p=.076), but none of the surgical outcomes were significantly different between groups. In regression analyses controlling for all measured variables, preoperative MRI was not predictive of any of the measured surgical outcomes.