No significant changes in capacity
“We didn’t see any significant changes in bladder capacity over time. We saw a really low complication rate and a really low 30-day readmission rate,” Kirk said. “We also saw only a single patient in our cohort develop new ulceration that wasn’t seen at their initial cystoscopy and hydrodistention.”
The complication rate with hydrodistention was <1%. The rate of 30-day readmission was 2%. The mean initial anesthetic bladder capacity was 723.9 cc, which was not significantly different from the final capacity of 753.1 cc (p=.15).
Among patients who completed AUA symptom questionnaires before and after hydrodistention, the symptom score improved from 17.1 before treatment to 14.3 post-hydrodistention (p<.001) and the quality of life score improved from 4.3 to 3.6 (p<.001).
“One of the things we want to do in the future, and what we’re working on, is building this database out to try to understand how we can predict who will benefit from hydrodistention,” Kirk told Urology Times. “We’re working to do multivariable modeling techniques to try to understand what the contributions of various clinical and demographic factors are in terms of being able to predict symptomatic response.”
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