• Benign Prostatic Hyperplasia
  • Hormone Therapy
  • Genomic Testing
  • Next-Generation Imaging
  • UTUC
  • OAB and Incontinence
  • Genitourinary Cancers
  • Kidney Cancer
  • Men's Health
  • Pediatrics
  • Female Urology
  • Sexual Dysfunction
  • Kidney Stones
  • Urologic Surgery
  • Bladder Cancer
  • Benign Conditions
  • Prostate Cancer

Botulinum injections may be effective in refractory OAB

Article

Detrusor botulism A (BTX-A) toxin injections may be an effective, safe treatment option in patients experiencing overactive bladder (OAB) refractory to other treatments, according to a Swiss study presented yesterday.

Detrusor botulinum A (BTX-A) toxin injections may be an effective, safe treatment option in patients experiencing overactive bladder (OAB) refractory to other treatments, according to a Swiss study presented yesterday.

One hundred patients with a mean age of 57 years (range 29 to 82 years) who were diagnosed with non-neurogenic OAB and incontinence, and who were previously treated with anticholingerics and physiotherapy received injections of 100 units of BTX-A at 20 sites in the detrusor muscle under cytoscopic control.

Data gathered included urodynamics, neurological status, urine probes and biopsies, and patient diaries before treatment, and patients received both clinical and urodynamic followup 6 to 8 weeks after treatment.

Study author Daniel M. Schmid, Jr., MD, reported that 88% of patients with overactive bladder showed significant (p

"BTX-A appears not only to appears to block neuromuscular transmission of acetylcholine, but it seems also to modulate bladder reflexes," Dr. Schmid concluded.

Related Videos
Blurred interior of hospital |  Image Credit: © jakkapan - stock.adobe.com
Laura Bukavina, MD, MPH, answers a question during a Zoom video interview
Image of kidneys | Image Credit: © peterschreiber.media - stock.adobe.com
Neal Shore, MD, FACS, and Brian M. Shuch, MD, experts on kidney cancer
Neal Shore, MD, FACS, and Brian M. Shuch, MD, experts on kidney cancer
Blur image of hospital corridor | Image Credit: © whyframeshot - stock.adobe.com
Related Content
© 2024 MJH Life Sciences

All rights reserved.