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Alan Bryce, MD, highlights key phase 3 advances in prostate cancerLatest News

Behind the FDA approval of belzutifan plus lenvatinib in advanced ccRCC, with Robert Motzer, MD

Brian Mazzarella, MD, reviews early data on water vapor therapy for localized prostate cancer

FDA grants fast track designation to pre-biopsy 68Ga-PSMA-PET program

Enzalutamide plus salvage radiotherapy associated with improved PFS in high-risk BCR

Armine K. Smith, MD, on addressing sexual health in modern bladder cancer care

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In the phase 3 PACE-A trial, SBRT and prostatectomy showed similar 8-year disease control in localized prostate cancer, with lower rates of urinary incontinence after SBRT.

Using PSMA-PET imaging and genomic testing to obtain better information earlier in the disease course changes what clinicians can do with diagnosis and treatment planning.

The registrational study is designed to evaluate the diagnostic performance of 68Ga-DOTA-RM2 vs histopathology in prostate cancer.

One year following the approval of the gemcitabine intravesical system, Joseph Jacob, MD, reflects on the expanding treatment landscape in BCG-unresponsive NMIBC.

A limited market release of SpaceOAR Flex is expected to begin in the US later this year.

The PDUFA target action date is in the fourth quarter of 2026.

FDA approves belzutifan plus lenvatinib for advanced clear cell renal cell carcinoma
The approval is supported by data from the phase 3 LITESPARK-011 trial.

Pearls & Perspectives: Expanding Sexual Health Conversations Through Digital Media, With Wendy Brant
Amy Pearlman, MD, and Wendy Brant discuss building a digital audience, navigating sexual health content online, and the role of communication in relationships.

Positive safety and efficacy data from 4 clinical studies supported the CE marking.

Sandip Prasad, MD, discusses patient selection for chemoablation in recurrent LG-IR-NMIBC and considerations when counseling patients about a nonsurgical approach.

In a head-to-head RCT, Rezūm produced a 4.6-point greater IPSS improvement than combination pharmacotherapy at 1 year, according to Jean-Nicolas Cornu, MD, PhD, FEBU.

The AACU and the WOCN Society urge CMS to protect access to individualized catheter and ostomy supplies as competitive bidding begins in 2028.

Better detection has changed prostate cancer care. Patients choosing radical treatment still need better protection from the disease returning.

Enfortumab vedotin-ejfv (Padcev) plus pembrolizumab (Keytruda) showed the strongest EFS, OS, and pCR associations among neoadjuvant MIBC strategies in a network meta-analysis, although perioperative design limits attribution.

Sandip Prasad, MD, MPhil, discusses the evolving role of chemoablation in recurrent low-grade, intermediate-risk NMIBC, including patient selection and treatment considerations.

































