Urine cytology NGS comparable to tumor biopsy in identifying UTUC mutations

Urine cytology specimen NGS was found to be a feasible and valid method of assessing genomic alterations in patients with upper tract urothelial carcinoma.

Segmental ureterectomy non-inferior to radical nephroureterectomy in high-risk UTUC

Findings presented at the 2021 Society of Urologic Oncology Annual Meeting demonstrate that segmental ureterectomy may be comparable to radical nephroureterectomy.

Re-TURBT prior to cystectomy has similar pathologic upstaging rates regardless of NAC status

The investigators found that the overall upstaging rate from re-TURBT to RC was 34.9%, with 31.0% upstaged in the NAC group and 37.0% in the no-NAC group (P = .584).