Kidney Cancer

FDA approves pembrolizumab across TMB-high solid tumors

June 17, 2020

Pembrolizumab has been granted a second tumor-agnostic FDA indication, this one for patients with solid tumors with a high tumor mutational burden.

Tivozanib May Be Superior Treatment for Patients With RCC, Study Finds

May 29, 2020

When compared with sorafenib, tivozanib showed improved progression-free survival, and a more manageable safety profile for patients with relapsed or refractory metastatic renal cell carcinoma.

RCC 2018: Systemic therapy landscape sees rapid change

January 18, 2019

Dr. Kutikov discuss several noteworthy studies about kidney cancer from 2018.

RCC 2018: Top advances in treatment of localized, advanced disease

January 18, 2019

"2018 was an exciting and productive year for kidney cancer research," write Amr A. Elbakry, MBBCh, MSc, and Ketan K. Badani, MD.

ISGF3 activation may inhibit tumor growth in clear cell RCC patients

December 03, 2018

Activating interferon stimulated gene factor 3 could be a new direction for treating clear cell renal cell carcinoma, according to a recent study.

Advanced RCC combo Tx significantly improves PFS

December 03, 2018

“The efficacy benefit and the favorable safety profile support aveluamb plus axitinib as a new first-line standard of care for advanced RCC,” says researcher Robert J. Motzer, MD.

Ablative RT could be alternative for solitary-kidney RCC

November 07, 2018

“We believe that referral for kidney SABR is worthy of consideration in patients with solitary-kidney RCC who are faced with limited and risky management options,” says researcher Rohann Correa, MD, PhD.

Could BMI predict mRCC treatment outcomes?

November 07, 2018

Body mass index appears to be a prognostic factor for treatment outcomes in patients with metastatic renal cell carcinoma, but the direction of the association might vary across treatment modalities.

Phase III RCC trial challenges current standard of care

October 26, 2018

"Proper patient selection, including those with low-/intermediate-risk disease, is paramount," writes Badar M. Mian, MD.

Challenging case: A large ‘ticking’ back lipoma and a small renal mass

October 23, 2018

The authors discuss the case of a 57-year-old man who initially presents to a general surgeon with a chief complaint of right lower back and posterior neck pain, with associated soft tissue swelling. On presentation to the authors' institution, he had experienced regrowth of the masses with "ticking" in the right lumbar area that he correlated with his heartbeat. He also reported unintentional weight loss of 15 pounds over the previous 3 months.