Benign Prostatic Hyperplasia

A recap of the FDA submissions and regulatory decisions in urology from December 2025.

As the year comes to a close, we revisit some of this year’s top content on benign prostatic hyperplasia.

Dean Elterman, MD, MSc, FRCSC, emphasizes that a key differentiator of this new class of devices lies in material science and mechanism of action.

Mechanistically, Kaplan emphasizes that ProVee’s key differentiator is not simply that it is an expanding urethral device, but that it belongs to a new class of flexible, catheter-like technologies.

Data from the pivotal BREEZE study indicated a mean IPSS improvement of 37% in patients receiving the system.

The approval is supported by results from the randomized ProVIDE study.

In determining the best treatment, urologist Arpeet Shah, MD, stresses the importance of thorough diagnostics.

Jaeger emphasized that the ideal HoLEP candidate is any patient with bothersome lower urinary tract symptoms due to BPH, including those with urinary retention or intolerance to medication

We recap notable headlines from last month in the benign urology space.

Martin B. Richman, MD, MBA, FACS, outlines recent advancements in BPH, with an emphasis on the importance of a patient-focused approach to care.

According to the authors, these findings suggest that FloStent could serve as an effective interim solution for men who are awaiting TURP.

Kanika Searvance, MD, and Yasin Bhanji, MD, discuss the evolution of BPH care.

Experts discuss the ways in which AI could transform patient care and improve physician workflows, particularly for benign prostatic hyperplasia.

Jennifer A. Robles, MD, MPH, discusses the future for HoLEP in terms of innovation and wider integration into urologic practice.

The presentations featured data on the drug candidate BOTRESO for BPH and LUTS, as well as on the prostate cancer prevention drug MCS-8.

"We are lucky to be in the position to offer so many treatment options customized to address [patients'] needs and help them enjoy life," says Kevin C. Zorn, MD, FRCSC, FACS.

Jennifer A. Robles, MD, MPH, highlights the impact of regional disparities in HoLEP access on patient care.

Jennifer A. Robles, MD, MPH, outlines 3 key factors that may be preventing more widespread adoption of HoLEP across the US.

Jennifer A. Robles, MD, MPH, highlights potential factors contributing to the surge in HoLEP utilization across the US.

Jennifer A. Robles, MD, MPH, discusses a study assessing trends and geographic disparities in HoLEP utilization across the United States.

However, M-HoLEP was superior in terms of enucleation time and efficiency, catheterization time, and hospital stay.

According to the authors, these data support Rezūm as an alternative first-line treatment option for patients at risk of BPH progression.

One consideration is the setting in which the procedure is performed.

Bilal I. Chughtai, MD, walks through the design and potential implications of a pivotal trial of the Butterfly Prostatic Device.

Here’s a look back at notable news between April and June 2025.