Current state of adjuvant immunotherapy for high-risk urothelial cancer
“This is the perfect situation for the development of biomarkers to inform [patient selection for] adjuvant treatment with immune checkpoint blockade,” says Matthew Galsky, MD.
In an interview at the 2022 SUO Annual Meeting, Matthew Galsky, MD, discussed the current state of the use of adjuvant immunotherapy for the treatment of patients with urothelial cancer at high risk of recurrence after radical surgery. Randomized clinical trials exploring the role of adjuvant immunotherapy in this setting have yielded somewhat mixed results, so Galksy says biomarkers are needed to determine optimal patient selection.
Galsky is a professor of Medicine and director of Genitourinary Medical Oncology at the Icahn School of Medicine, Mount Sinai, and the co-director of the Center of Excellence for Bladder Cancer and associate director for translational research at the Tisch Cancer Institute.
Lenvatinib/pembrolizumab compares favorably with frontline standards in renal cell carcinoma
February 2nd 2024“Combination therapy with lenvatinib plus pembrolizumab provides a comparable OS, and a trend of improvement in PFS and response outcomes, compared with most current global SOC therapies for treatment-naïve patients with advanced renal cell carcinoma,” the study authors wrote.
First-line pembrolizumab/lenvatinib shows efficacy for advanced non–clear cell RCC
January 29th 2024“Updated efficacy and safety results continue to support pembrolizumab plus lenvatinib as a first-line treatment option for patients with advanced non–clear cell RCC,” lead study author Martin H. Voss, MD.
