Katie Murray, DO, urologic oncologist and assistant professor of Urology at the University of Missouri, discusses findings from a real-world study of antegrade administration of reverse thermal mitomycin gel (Jelmyto) for primary chemoablation of upper tract urothelial carcinoma via percutaneous nephrostomy tube. The study, which was presented at the 2022 AUA Annual Meeting (abstract PD58-06), sought to analyze whether antegrade administration of Jelmyto might decrease some of the comorbidity and complications reported in the pivotal OLYMPUS trial that led to the FDA approval of the treatment.
KIM-1 emerges as biomarker for MRD, atezolizumab benefit in renal cell carcinoma
June 3rd 2024Circulating kidney injury molecule-1 (KIM-1) may be a biomarker for minimal residual disease, disease recurrence, and benefit from adjuvant atezolizumab in patients with renal cell carcinoma at increased risk of recurrence, according to a retrospective analysis of the phase 3 IMmotion010 trial.