Dr. Pal on next steps with cabozantinib/atezolizumab in bladder cancer

Sumanta K. Pal, MD, City of Hope Comprehensive Cancer Center, discusses next steps for the combination of cabozantinib (Cabometyx) and atezolizumab (Tecentriq) in patients with bladder cancer. At the 2022 ASCO Annual Meeting Pal shared results from the phase 1b COSMIC-021 trial showing promising activity in patients with urothelial carcinoma who had no prior systemic therapy and were cisplatin ineligible; had no prior systemic therapy but were cisplatin eligible, or had received 1 prior immune checkpoint inhibitor, were VEGFR-TKI–naïve, and had received ≤2 lines of therapy overall.