Sumanta K. Pal, MD, City of Hope Comprehensive Cancer Center, discusses next steps for the combination of cabozantinib (Cabometyx) and atezolizumab (Tecentriq) in patients with bladder cancer. At the 2022 ASCO Annual Meeting Pal shared results from the phase 1b COSMIC-021 trial showing promising activity in patients with urothelial carcinoma who had no prior systemic therapy and were cisplatin ineligible; had no prior systemic therapy but were cisplatin eligible, or had received 1 prior immune checkpoint inhibitor, were VEGFR-TKI–naïve, and had received ≤2 lines of therapy overall.
Speaking of Urology Podcast: Dr. Ritch and Dr. Katz discuss new bladder cancer management app
December 7th 2021“It's not a replacement for clinical judgment, obviously. But at the end of the day, the idea is that it shows you what your next steps are based on what the American Urological Association and [Society of Urologic Oncology] guidelines are for non-muscle invasive bladder cancer,” Chad R. Ritch, MD, MBA, FACS.
Cell therapy TARA-002 shows initial promise in NMIBC
April 9th 2024"This encouraging anti-tumor activity coupled with a favorable safety profile and mode of administration that is both convenient and familiar to urologists indicates that, if confirmed in future studies, TARA-002 could potentially play a meaningful role in NMIBC treatment in the future," says Timothy D. Lyon, MD.