Is it time to lower the PSA cut-point for biopsy?

Chicago-The traditional PSA cut-point of 4.0 ng/mL for recommending abiopsy to diagnose prostate cancer is controversial, and some researchershave recommended cut-points as low as 2.0 ng/mL. Two separate studies presentedat the AUA annual meeting here have found that cut-points of 2.5 or 2.6ng/mL may be more appropriate for determining the need for prostate biopsy.