
The investigational HIF-2α inhibitor casdatifan demonstrated antitumor activity as monotherapy and in combination regimens across the ARC-20 platform study.
Bradley McGregor, MD, explains patient considerations that come into play now that there are several promising treatment options, such as dual immunotherapy combos and immunotherapy/TKI combos, in the frontline setting for the treatment of patients with renal cell carcinoma. McGregor is clinical director, Lank Center for Genitourinary Oncology, senior physician, instructor in Medicine, Harvard Medical School, Dana-Farber Cancer Institute.