Other infection/inflammation take-home messages from the AUA annual meeting include a study of predictors of fluoroquinolone resistance in the rectal vault of men undergoing prostate biopsy and a study of 1,310 patients evaluated over 16 years for CP/CPPS.
Sarah Coleman Flury, MDOther infection/inflammation take-home messages from the AUA annual meeting include a study of predictors of fluoroquinolone resistance in the rectal vault of men undergoing prostate biopsy and a study of 1,310 patients evaluated over 16 years for CP/CPPS. The take-home messages were presented by Sarah Coleman Flury, MD, of Northwestern University, Chicago.
A cost-effectiveness analysis of targeted antimicrobial therapy in TRUS-guided prostate biopsy showed that use of rectal swabs prior to biopsy reduced costs, led to fewer infections, and improved patient quality of life.
The rate of infective complications after transrectal ultrasound (TRUS)-guided prostate biopsy increased significantly after transition to single-dose oral ciprofloxacin (Cipro) prophylaxis.
A study of predictors of fluoroquinolone resistance in the rectal vault of men undergoing prostate biopsy identified increasing age, recent antibiotic use, African-American and Hispanic race, and higher rates of benign pathology, including BPH and inflammation.
Potential risk factors to guide targeted screening for fluoroquinolone-resistant Escherichia coli in bowel flora are not sufficiently discriminatory to identify a specific high-risk group, supporting a case for prebiopsy rectal swab in all patients.
A prospective cohort trial of targeted antimicrobial prophylaxis before prostate biopsy used results of individual rectal flora cultures to drive antibiotic choice, resulting in a low rate of infectious complications, limited morbidity, and no sustained sequelae.
Continue to the next page for more take-home messages.
Next: An analysis of urinary markers in women with IC/BPS
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