Prostate cancer genome viewed with powerful technique

New York-Prostate cancer research using whole genome sequencing analysis may lead to the identification of novel therapeutic targets as well as diagnostic tools for identifying aggressive primary tumors and characterizing genomic changes associated with disease progression.

To characterize prostate cancer genomic alterations, parallel sequencing of the entire genome was performed using normal tissue and tumor specimens from seven men with high-risk primary prostate cancer who underwent robotic radical prostatectomy performed by Ashutosh Tewari, MD, of Weill Cornell Medical College.