Prostate cancer incidence found similar in low, higher PSA ranges
ChicagoA retrospective study of more than 36,000 prostate cancerbiopsies found, as expected, that the incidence of prostate cancer variedaccording to PSA levels. But the study's authors also found that the incidenceof prostate cancer was similar for men with PSAs between 2.5 and 4.0 ng/mLand those with PSAs between 4.0 and 10.0 ng/mL.
Abraham Morgentaler, MD, reviews evidence showing no association between testosterone therapy and prostate cancer risk and explains the saturation model of androgen action.
Mark D. Tyson, II, MD, MPH, reviews emerging bladder-sparing therapies for NMIBC, highlighting cretostimogene data, treatment sequencing, and the need for comparative trials.
Peter Clark, MD, discusses key updates to NMIBC guidelines, including revisions to risk stratification, the emerging role of biomarkers, and how to navigate treatment options for BCG-unresponsive disease.