Author | Laszlo Dosa

Articles

Highly toxic chemo may be effective in bladder TCC

October 01, 2006

Article

Atlanta-Neoadjuvant chemotherapy using a three-drug combination has demonstrated activity in locally advanced transitional cell carcinoma (TCC) of the bladder, but it also possesses considerable toxicity. That was the conclusion reported in a poster by University of Michigan researchers at the American Society of Clinical Oncology annual meeting.

Studies document new agent's efficacy in advanced RCC

September 01, 2006

Article

Atlanta-Two recent studies have provided promising outcomes data on sorafenib tosylate (Nexavar), both as a second-line therapy and potentially as first-line treatment in patients with advanced renal cell carcinoma, researchers reported at the American Society of Clinical Oncology annual meeting here.

Agent shows superior safety as first-line RCC therapy

September 01, 2006

Article

Atlanta-Sorafenib tosylate (Nexavar), a newer oral multi-kinase inhibitor that targets tumor growth and vascularization, was generally well tolerated by patients with metastatic clear-cell renal cell carcinoma in a randomized phase II trial that compared the efficacy and tolerability of the drug with that of interferon in first-line therapy. Study results were presented by Bernard Escudier, MD, head of the immunotherapy and innovative therapy unit at Institut Gustave Roussy Villejuif, Cedex, France, at the American Society of Clinical Oncology annual meeting here.

Monoclonal antibody cited for activity against RCC

September 01, 2006

Article

Atlanta-Contrary to earlier data from a single-arm study, the addition of erlotinib (Tarceva) to the monoclonal antibody bevacizumab (Avastin) does not significantly delay disease progression in patients with metastatic renal cell carcinoma, according to data presented at the American Society of Clinical Oncology annual meeting. The new findings suggest that bevacizumab is responsible for increasing progression-free survival in this patient population.