San Francisco—Nocturia appears to be highly prevalent in the United States, with almost 30% of all women reporting significant nocturia, according to new data reported at the AUA annual meeting in San Francisco.
Researchers mined data from the National Health and Nutrition Examination Survey (NHANES) database and found that among all women surveyed, 28.8% reported significant nocturia.
The authors analyzed data on 7,620 women and found that nocturia rates increased with increasing age (p<.0001). In addition, among those women who underwent childbirth, delivery type had no association with nocturia (p=.23). The investigators conducted a multivariable analysis and found that only increasing age (odds ratio [OR]: 1.8), African-American race (odds ratio: 2.35), body mass index ≥30 (odds ratio: 1.5), urge incontinence (OR: 1.6), and poor overall health (OR: 1.48) were associated with increased rates of nocturia.
“Urge incontinence and poor health status correlated with nocturia,” said study author Timothy Byler, MD, assistant professor of urology at SUNY Upstate Medical University, Syracuse, NY. “In terms of medical comorbidities associated with nocturia, depression, hypertension, and arthritis were highly associated.”
Obstetrical history not associated
Dr. Byler, who presented the study findings, said obstetrical history was found to have no association with nocturia. Factors not associated with nocturia were hysterectomy, prolapse, oophorectomy, menopause, and delivery type. He said the findings, while intriguing, are limited by their retrospective nature.
“There are certain limitations due to recall bias and survey bias,” said Dr. Byler.
Nocturia can be one of the most bothersome lower urinary tract symptoms that can significantly affect quality of life. In both men and women, nocturia has been associated with decreased overall health, but little evidence exists on the prevalence of nocturia in U.S. females.
“There is a lot of focus on male nocturia and treatment for it, but there is not a lot in the literature on female nocturia and how common it is,” Dr. Byler said in an interview with Urology Times.