February 25th 2020
Urologists must differentiate between bladder outlet obstruction and pure OAB in male patients, according to Osvaldo F. Padron, MD.
January 30th 2019
Minimally invasive surgical options took front and center in 2018 when the AUA published its revised guideline on the surgical management of male lower urinary tract symptoms secondary to BPH.
January 3rd 2019
Convective radiofrequency water vapor thermal therapy (Rezum) can modestly improve symptoms of BPH, according to Daniel Mollengarden, MD.
November 20th 2018
Procedure safest when performed in <60 minutes.
A recent study found that sacral neuromodulation monotherapy was efficacious as a third-line treatment.
Nearly 30% of U.S. women report nocturia
Nocturia appears to be highly prevalent in the United States, with almost 30% of all women reporting significant nocturia, according to new data reported at the AUA annual meeting in San Francisco.
Data shift thinking on nocturia’s causes, treatment
Waking up at night to urinate is by far the most bothersome lower urinary tract symptom.
BPH procedures and med use: Two sides of a coin
"When analyzing efficacy of minimally invasive/surgical therapies for lower urinary tract symptoms secondary to BPH, we appropriately focus on subjective criteria and objective criteria. While we discuss retreatment rates, we don’t measure failure of therapies by how many men restart LUTS/BPH medications," writes Steven A. Kaplan, MD.
Which BPH procedures best reduce need for meds?
Tissue-eliminating procedures outperform tissue-necrosing procedures for reducing the need for medication in patients with benign prostatic enlargement, researchers say.
Non-head MRI found safe in patients undergoing SNM
The therapeutic efficacy of sacral neuromodulation was not affected by non-head magnetic resonance imaging scans in a recent study.
More than 50% of patients stop botulinum treatment
Over half of patients stop intradetrusor botulinum toxin injections within 10 years, mostly due to lack of clinical efficacy, researchers say.
Urethral lift efficacious in men with large median lobe
Results of the prospective MedLift study establish the efficacy and safety of the Prostatic Urethral Lift (PUL [UroLift System]) procedure for treatment of symptomatic BPH in men with an enlarged median lobe.
Live demos of prostate procedure found safe
Performing green laser enucleation of the prostate with a live audience does not result in more complications, researchers say.
Waterjet fares better vs. TURP in large prostates
Men with large prostates experience more relief from BPH with treatment by Aquablation therapy (using the AquaBeam System) than with transurethral resection of the prostate, researchers say.
Alcohol and the prostate gland: Friend or foe?
Studies show moderate alcohol intake has surprising links to prostate disease.
Outcomes: What drives cost variation for urologic Ca surgery?
The AUA 2018 take-home messages in outcomes also covered topics such as environmental exposures and bladder cancer and onabotulinumtoxinA (Botox) treatment for patients with overactive bladder.
Depression and suicide in men: Identifying the risk
This article discusses the risk of depression and suicide in men, focusing on increased risk in men with genitourinary cancer and other urologic conditions.
BPH treatments’ cost-effectiveness put to test
Findings from a cost-effectiveness analysis provide useful information for physicians, patients, and payers about available treatments for lower urinary tract symptoms due to BPH, according to the authors who conducted it.
Simple prostatectomy for BPH: Surgeons demonstrate robotic approaches
These videos illustrate a robotic solution to the complex problem of very large prostate glands causing severe lower urinary tract symptoms.
Metallic stents efficacious for malignant ureteral obstruction
A new study suggests that metallic Resonance ureteral stents are a good option for management of malignant ureteral obstruction because they promote strong long-term outcomes.
Racial disparity seen with SUI surgical restoration
In another potential sign of racial disparities in urologic care, a new study finds that urologic restoration surgery is significantly less likely to be used to treat African-American men with stress urinary incontinence than Caucasian men, although African-Americans appear to have higher rates of SUI.
New Products: BPH surgical robot granted FDA de novo request
Other products highlighted in this round-up include a plate for studying infections caused by the long-term use of catheters and a new indication for sunitinib malate (SUTENT).
Study: Monopolar TURP utilization on the decline
Although monopolar transurethral resection of the prostate remains the standard of care for bladder outlet obstruction secondary to BPH, its utilization has decreased in recent years, according to a recent study.
Combined imaging technique feasible in POP repair
Reconstruction of anterior compartment defects using magnetic resonance-visible vaginal mesh implants in combination with post-surgical three-dimensional imaging is feasible and yields reproducible results, researchers report.
Urethroplasty delay results in more complex repair
Delay to urethroplasty for bulbar urethral strictures is associated with repetitive interventions, stricture lengthening, and more complex repairs that have a greater risk for failure, while scheduling-related delay to reconstruction exposes men to risk for stricture-related complications, according to separate studies presented at the AUA annual meeting in Boston.
Uro Pipeline: NDA submitted for non-metastatic castration-resistant PCa agent
Other pipeline products discussed in this round-up include and advanced renal cell carcinoma agent, a bladder cancer detection agent, and a BPH treatment.
IC/BPS: One-fourth of patients have Hunner lesions
About one-fourth of patients with interstitial cystitis/bladder pain syndrome have Hunner lesions in the bladder visible on cystoscopy.
SNS vs. botulinum: Caveats, considerations
Repeat hydrodistention found safe in treating IC
Repeated hydrodistention as therapy for interstitial cystitis has a low complication rate and does not decrease bladder capacity over time.
Bother, symptom severity often poorly correlated in LUTS
The correlation between patient-reported bother and symptom severity is inexact, according to conclusions of a recent retrospective multicenter study of nearly 1,200 patients referred for lower urinary tract symptoms.
SUI: Phase III data offer lessons for trials evaluating cell therapy
Results of one of the first randomized controlled trials evaluating cell therapy for women with stress urinary incontinence (SUI) has helped to identify clinically meaningful efficacy endpoints to refine patient selection criteria for current and future studies, according to investigator Melissa R. Kaufman, MD, PhD.
New Products: FDA approves treatment for complicated UTI
Other products and services discussed in this round-up include a biosimilar for cancer, an American College of Surgeons manual on quality initiatives, a kidney cancer microsite, and more.
Waterjet ablation confers advantages over TURP
Heat-free high-velocity waterjet ablation (Aquablation) for BPH performed with an image-guided robot-assisted platform (AquaBeam System) met its primary safety and efficacy endpoints in a phase III study.
Water vapor ablation yields positive results at 2 years
Treatment of lower urinary tract symptoms/BPH with convective water vapor ablation (Rezum System) appears to provide significant improvement on two key outcome measures versus medical therapy at up to 2 years, according to a study presented at the AUA annual meeting in Boston.
5-ARI use does not raise erectile dysfunction risk
The risk of erectile dysfunction is not increased with the use of a 5-alpha-reductase inhibitor compared with an alpha-blocker for the treatment of BPH.
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