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In older patients, antidiuretic drug reduces nocturnal voiding by more than 50%

Alpha-blocker, PDE-5 combo doesn't lead to CV events

San Francisco--A commonly prescribed antibiotic and alpha-blocker appear to be ineffective in the treatment of men with moderate to severe chronic prostatitis/chronic pelvic pain syndrome of long duration. Results of a multicenter study found that both ciprofloxacin and tamsulosin-used primarily in the treatment of urinary tract infections and BPH, respectively-offered no significant benefit in the treatment of chronic prostatitis in patients who were heavily pretreated and had long-standing symptoms.

Sequential monotherapy yields poor results in CPPS

The Centers for Medicare & Medicaid Services and the National Cancer Institute have developed a joint Memorandum of Understanding to address how the two agencies can work together in five areas of technology, science, and patient care for cancer.

Four leading prostate cancer advocacy groups are working in cooperation with the FDA to streamline the approval process of critical prostate cancer treatments by changing clinical trial endpoints, without compromising safety.

The FDA issued an approvable letter for a sustained-release formulation of doxazosin mesylate (Cardura XL), an alpha-blocker used to treat BPH.

Prostate cancer patients who receive radiotherapy within 6 months of surgery live longer than those who do not receive radiotherapy, according to an Italian study appearing in the Journal of Radiation Oncology, Biology, and Physics (2004; 59:674-83).

Flexibility, negotiation, and goodwill can keep on-call tensions to aminimum

Often tell staffers how they're performing, and listen to their job-related concerns

AUA guideline warns of conflicts of interest influencing PDE-5 comparison trials

Settlements create monetary funds, prevent companies from engaging in harmful practices

Sexual dysfunction and BPH appear to be strongly associated in older men, according to two new studies.

Regardless of whether it is given adjuvantly or as salvage therapy, radiation therapy reduces the likelihood of prostate cancer recurrence, according to a study in the International Journal of Radiation Oncology, Biology, Physics (2004; 59: 329-40).

Trospium chloride (Sanctura) has been approved by the FDA for the treatment of overactive bladder with symptoms of urge incontinence, urgency, and urinary frequency.

Men who have a low PSA level according to standard PSA testing can still have prostate cancer, according to a recent study in the New England Journal of Medicine (2004; 350:2239-46).

NMP22 test plus cytology may hold potential for tailoring cystoscopic follow-up

San Francisco-Some herbal supplements marketed for erectile dysfunction are not nearly as "safe and effective" as they are touted to be, say concerned experts.

‘TAP’ is used when curvature is

San Francisco--Second-look nephroscopy following percutaneous nephrolithotomy (PNL) could be supplanted by metabolic evaluation and aggressive medical therapy, said researchers from the Duke University Medical Center. Second-look nephroscopy is currently the gold standard for assessing and achieving stone-free status, but the Duke researchers sought to determine whether this additional procedure was necessary.

Lithotripsy is generally excluded, but watch for indirect financial relationships

Studies of the effect of chemotherapy in men with metastatic prostatecancer have been enticing and, at the same time, disappointing. While showingPSA response in some cases, these studies have previously failed to demonstrateimproved survival. This is all about to change, and for the better. We areentering an exciting new era in the management of this patient population.

'Substitute checks' will clear the bank electronically, speeding up transactions

Here's how to code when LHRH injection, cystoscopy, and biopsy are providedon the same day

San Francisco--Continuing a trend of mixed results seen in previousstudies, neoadjuvant chemotherapy with docetaxel (Taxotere) resulted ina significant PSA response but failed to induce any histologic changes inlocally advanced prostate cancer, Cleveland Clinic investigators reportedat the AUA annual meeting.

Oceanside, NY--In men with clinically localized prostate cancer,monotherapy with radical prostatectomy, external beam radiation therapy,or permanent prostate brachytherapy offer the same excellent chance of biochemicalsuccess, according to the results of a large, retrospective study.

San Francisco--Still known primarily for its ability to smoothfacial wrinkles, botulinum toxin A (Botox) is gaining acceptance as a treatmentoption for refractory overactive and neurogenic bladder.

Vanilloid is shown to improve urgency but not pain, leakage, nocturia, or enuresis