Anti-androgen shows benefit as adjuvant PCa therapy
Vienna, Austria--The first analysis of the Early Prostate Cancer program-presented3 years ago at the European Association of Urology annual congress-revealedthat the anti-androgen bicalutamide (Casodex), 150 mg, cuts prostate cancerprogression risk almost in half in patients with localized or locally advanceddisease. A second analysis, presented at this year's meeting, confirmedthat the earlier finding holds true whether patients are treated with radicalprostatectomy, radiotherapy, or watchful waiting.
Abraham Morgentaler, MD, reviews evidence showing no association between testosterone therapy and prostate cancer risk and explains the saturation model of androgen action.
Mark D. Tyson, II, MD, MPH, reviews emerging bladder-sparing therapies for NMIBC, highlighting cretostimogene data, treatment sequencing, and the need for comparative trials.