Madrid, Spain-Botulinum-A toxin shows positive results as an alternativetreatment of neurogenic detrusor overactivity when oral therapies or intravesicalanticholinergics fail or are intolerable, according to results of four separatestudies presented at the European Association of Urology 18th congress here.The agent, although FDA-approved for the treatment of skin wrinkles andrelated indications, is not approved for detrusor overactivity but has beenused by some U.S. and European urologists for this indication.
Engy Habashy, MD, discusses key takeaways from the 2025 AUA GSM guideline, including the role of androgens and hormonal therapies in managing genitourinary syndrome of menopause.
Chad R. Ritch, MD, MBA, FACS, discusses how PSMA-PET informs staging, treatment planning, recurrence workup, and the interpretation of equivocal findings.
Michael S. Cookson, MD, MMHC, FACS, discusses how Anktiva’s expanded FDA approval may broaden bladder-preserving treatment options for BCG-unresponsive papillary-only NMIBC.
The investigational HIF-2α inhibitor casdatifan demonstrated antitumor activity as monotherapy and in combination regimens across the ARC-20 platform study.