Botulinum toxin shows promising results in refractory OAB
Known primarily for smoothing facial wrinkles, botulinumtoxin A (Botox) is gaining acceptance as a treatment option for refractoryoveractive and neurogenic bladder. The latest evidence comes from the Universityof Pittsburgh School of Medicine, where a 110-patient review of the off-labeluse of botulinum toxin for those indications produced promising resultsin terms of both safety and efficacy.
Abraham Morgentaler, MD, reviews evidence showing no association between testosterone therapy and prostate cancer risk and explains the saturation model of androgen action.
Mark D. Tyson, II, MD, MPH, reviews emerging bladder-sparing therapies for NMIBC, highlighting cretostimogene data, treatment sequencing, and the need for comparative trials.