• Benign Prostatic Hyperplasia
  • Hormone Therapy
  • Genomic Testing
  • Next-Generation Imaging
  • UTUC
  • OAB and Incontinence
  • Genitourinary Cancers
  • Kidney Cancer
  • Men's Health
  • Pediatrics
  • Female Urology
  • Sexual Dysfunction
  • Kidney Stones
  • Urologic Surgery
  • Bladder Cancer
  • Benign Conditions
  • Prostate Cancer

Dr. Arenas-Gallo highlights findings on DNA alteration frequency in Hispanic men with prostate cancer


"What we found was a very different frequency of alterations in important genes," says Camilo Arenas-Gallo, MD.

In this video, Camilo Arenas-Gallo, MD, discusses findings from the study, “Prostate Cancer Genetic Alterations in Hispanic Men,” which were presented at the 2023 American Urological Association Annual Meeting in Chicago, Illinois. Arenas-Gallo is a research fellow at Case Western Reserve University in Cleveland, Ohio.

Video Transcript:

What we did is, compiling this data that is publicly available, as I said in GENIE, [we tried] to [look at] Hispanic Whites [and] Hispanic Blacks, compared to non-Hispanic Whites and non-Hispanic Black men. Unfortunately, the database doesn't have a lot of Hispanic Blacks, so we had to remove that from our dataset. So, it's mostly self-identified Hispanic White men.

What we found was a very different frequency of alterations in important genes. For example, DNA genes that do DNA repair or genes that have been correlated with worse outcomes in men with prostate cancer. We found interesting differences between the Hispanic population with non-Hispanic Whites and Blacks, but we also found very interesting similarities. Probably the most important is that the actionable mutations that you can actually develop drugs or target therapies [from] is very similar. We didn't find any significant differences, which means that developing a targeted therapies is going to be beneficial for a high percentage of Hispanic men.

This transcription has been edited for clarity.

Related Videos
Blurred interior of hospital |  Image Credit: © jakkapan - stock.adobe.com
Laura Bukavina, MD, MPH, answers a question during a Zoom video interview
Image of kidneys | Image Credit: © peterschreiber.media - stock.adobe.com
Blur image of hospital corridor | Image Credit: © whyframeshot - stock.adobe.com
DNA helix | Image Credit: © Siarhei - stock.adobe.com
Related Content
© 2024 MJH Life Sciences

All rights reserved.