Robert A. Figlin, MD, deputy director, Cedars-Sinai Cancer, discusses remaining questions from the phase 3 KEYNOTE-564 trial, which was presented at the 2021 ASCO Annual Meeting (LBA5). The study findings showed that adjuvant pembrolizumab (Keytruda) led to a significant reduction in the risk of disease recurrence or death versus placebo in patients with clear cell renal cell carcinoma. In the video, Figlin shares his expert observations on important questions that still remain, despite the positive results of the trial.
KIM-1 emerges as biomarker for MRD, atezolizumab benefit in renal cell carcinoma
June 3rd 2024Circulating kidney injury molecule-1 (KIM-1) may be a biomarker for minimal residual disease, disease recurrence, and benefit from adjuvant atezolizumab in patients with renal cell carcinoma at increased risk of recurrence, according to a retrospective analysis of the phase 3 IMmotion010 trial.