Dr. Rooker discusses third-line therapies for men with OAB


“I definitely am more careful about who I offer Botox to in men,” says Gina M. Rooker, MD.

In this video, Gina M. Rooker, MD, shares insight on third-line therapy options for patients with overactive bladder (OAB), specifically highlighting the use of onabotulinumtoxin A (Botox) in male patients. Rooker is a urologist at Allegheny Health Network in Pittsburgh, Pennsylvania.

Video Transcript:

I look at things a little bit differently in the male population because my experience with bladder Botox in men is that even if they've been on fairly large doses of antimuscarinics, or antimuscarinics and β3 agonists, a small amount of Botox will put them into urinary retention if they have a prostate. I will consider Botox in a patient who's had a prior prostatectomy. We do have a lot of prostatectomy patients who have underlying overactive bladder. That comes to light after they've had their prostate removed for cancer, and then they have frequency urgency urge incontinence. So, Botox can be effective in that population. But I definitely am more careful about who I offer Botox to in men. In the male population, if they have an intact prostate and they have a lot of frequency urgency, it's clearly overactive bladder, then I'm more likely to do an InterStim trial on them, because at least I'm not going to make their voiding dysfunction worse with the treatment.

This transcription has been edited for clarity.

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