Exploratory analyses suggest persistent immune remodeling after aglatimagene plus radiation in localized prostate cancer.
|Videos|January 4, 2023
Dr. Tanya Dorff on latest progress with PARP inhibitors in mCRPC
Author(s)Urology Times staff
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Tanya Dorff, MD, discusses 3 pivotal trials—PROpel, MAGNITUDE, TALAPRO-2 trial—examining the potential of combining PARP inhibitors with androgen receptor–targeted agents in patients with metastatic castration-resistant prostate cancer. Dorff is a medical oncologist, section chief of Genitourinary Disease Program, and associate professor in the Department of Medical Oncology & Therapeutics Research at City of Hope Comprehensive Cancer Center.
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Brian Mazzarella, MD, discusses the landscape for intermediate-risk prostate cancer and early VAPOR 2 findings on water vapor ablation.
The phase 3 BiPASS trial is evaluating the use of 68Ga-PSMA-PET in combination with MRI for pre-biopsy prostate cancer detection.
In RTOG 3506, adding enzalutamide to standard ADT and salvage radiotherapy was associated with 2-year PFS benefit.
In the phase 3 PACE-A trial, SBRT and prostatectomy showed similar 8-year disease control in localized prostate cancer, with lower rates of urinary incontinence after SBRT.
Using PSMA-PET imaging and genomic testing to obtain better information earlier in the disease course changes what clinicians can do with diagnosis and treatment planning.
The registrational study is designed to evaluate the diagnostic performance of 68Ga-DOTA-RM2 vs histopathology in prostate cancer.
A limited market release of SpaceOAR Flex is expected to begin in the US later this year.
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