Periurethral bulking agents provide a unique, minimally invasive treatment option for stress urinary incontinence in female patients. Although many different injectable agents have been described, the gold standard remains glutaraldehyde cross-linked bovine collagen (Contigen). Limited efficacy and durability have been reported in a significant proportion of patients and presumed to result from collagen loss (eg, by tissue absorption/metabolism and luminal extravasation).
Current 3-D US data Close to two-thirds (62%) of patients who have achieved an initial satisfactory improvement in continence have been shown to have a circumferential distribution of collagen around the urethra, while this configuration was observed in only 20% of patients without satisfactory improvement in continence (Urology 2003; 62:232-6). Eighty percent of patients achieving a durable response (at least 1 year; mean, 2 years) had a circumferential configuration (Urology 2005; 65:60-6).
Malpractice Consult: How likely are you to face a medical malpractice lawsuit?
July 23rd 2024"Although there is a good chance that you will face allegations of medical negligence at some point in your career, it is unlikely that you will ever be found liable by a jury," writes Victoria L. Neikam, Esq.
UK study of AI-based software for prostate cancer detection expands
July 22nd 2024"We will be looking not only at how well this software performs in a busy clinical setting and whether diagnostic accuracy and efficiency improves, but also assessing the experience of clinicians and patients, and looking at the impact on workflow," says Clare Verrill, BM, FRCPath, MMedEd.