Chicago-Women with stress urinary incontinence receiving an investigationalagent designed to inhibit two key neurotransmitters significantly showeda reduced number of weekly incontinence episodes and improvements in qualityof life compared with patients receiving placebo. The drug, duloxetine,is dual reuptake inhibitor of serotonin and norepinephrine currently inphase III development.
Engy Habashy, MD, discusses key takeaways from the 2025 AUA GSM guideline, including the role of androgens and hormonal therapies in managing genitourinary syndrome of menopause.
Chad R. Ritch, MD, MBA, FACS, discusses how PSMA-PET informs staging, treatment planning, recurrence workup, and the interpretation of equivocal findings.
Michael S. Cookson, MD, MMHC, FACS, discusses how Anktiva’s expanded FDA approval may broaden bladder-preserving treatment options for BCG-unresponsive papillary-only NMIBC.
The investigational HIF-2α inhibitor casdatifan demonstrated antitumor activity as monotherapy and in combination regimens across the ARC-20 platform study.