Neoadjuvant chemo reduces bladder Ca mortality

Orlando, FL-After 7 years follow-up, researchers from the UnitedKingdom report that a landmark clinical trial in bladder cancer now showsa significant reduction in mortality if patients underwent 3 months of neoadjuvantchemotherapy prior to definitive surgery or radiation for muscle-invasivebladder cancer.

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April 1st 2021

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The ILLUMINATE-A trial of lumasiran in patients with primary hyperoxaluria type 1 supported the FDA approval of this drug.

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The RNAi drug nedosiran is a once-monthly subcutaneous injection under investigation for all 3 types of primary hyperoxaluria.

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Jason M. Broderick

FDA new drug application filing expected by the end of 2021.

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FDA approves androgen inhibitor for metastatic PCa

The FDA recently approved the oral androgen receptor inhibitor enzalutamide (Xtandi) for the treatment of patients with metastatic castration-resistant prostate cancer who have previously received docetaxel (Taxotere).

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A common enzyme that is easily detected in blood may predict how well patients with advanced kidney cancer will respond to a specific treatment, according to physicians at Duke Cancer Institute, Durham, NC.

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