Partial nephrectomy helps preserve bone health

Article

Patients who undergo radical nephrectomy experience a significantly higher incidence of osteoporosis and fractures when compared with those who undergo partial nephrectomy, according to a recent study.

Patients who undergo radical nephrectomy experience a significantly higher incidence of osteoporosis and fractures when compared with those who undergo partial nephrectomy, according to a recent study.

"When weighing the risks and benefits of partial versus radical nephrectomy, doctors and patients should take into account the impact on a patient’s bone health," said senior author Ithaar Derweesh, MD, of the University of California, San Diego School of Medicine.

"This study illuminates the fact that preserving the kidney helps to prevent chronic kidney disease and significantly reduces bone fractures and risk of developing osteoporosis."

In their retrospective review of 905 patients, Dr. Derweesh and colleagues found significantly less postoperative osteoporosis in the partial nephrectomy cohort (12.5% vs. 22.6%, pp=.007). Female gender, Caucasian race, preoperative glomerular filtration rate

Radical nephrectomy is a significant risk factor for chronic kidney disease, which itself carries increased risk for metabolic complications, cardiovascular disease, and death. Partial nephrectomy leaves behind functional tissue and healthy cells that can help prevent or reduce the risk of metabolic disease leading to kidney dysfunction, muscle atrophy, and osteoporosis.

"Women facing kidney surgery should investigate whether partial kidney removal is an option to treat their disease, as it may help prevent bone brittleness," said co-author Christopher Kane, MD, of UCSD.

Results of the study were published online in Urology (July 19, 2011).

Related Videos
 Licensed   FILE #:  458906503  Preview Crop  Find Similar  Expand Image DIMENSIONS 8000 x 5333px FILE TYPE JPEG CATEGORY The Environment LICENSE TYPE Standard or Extended A lake in the shape of a recycling sign in the middle of untouched nature | Image Credit: © malp - stock.adobe.com
Dr. Mehmet Asim Bilen in an interview with Urology Times
Anne M. Suskind, MD, MS, FACS, FPMRS, answers a question during a Zoom video interview
blurred clinic hallway
Female doctor using laptop | Image Credit: © nenetus - stock.adobe.com
Related Content
© 2024 MJH Life Sciences

All rights reserved.