Pediatric UTI marker, post-surgery antimicrobial prophylaxis among infection studies to watch for

April 17, 2014

In discussing research at the 2014 AUA annual meeting, Anthony J. Schaeffer, MD, called attention to an important paper concerning urinary tract infection in children, as well as another study showing that antimicrobial prophylaxis after surgery is subject to considerable variation.

This article is part of the State of Urology 2014

Dr. SchaefferIn discussing research at the 2014 AUA annual meeting, Anthony J. Schaeffer, MD, called attention to an important paper concerning urinary tract infection in children, this one in the realm of diagnosis.

“At this meeting, attendees will learn about a new marker for susceptibility to urinary tract infection in children,” said Dr. Schaeffer, professor and chair of urology at the Northwestern University Feinberg School of Medicine, Chicago. “Children more susceptible to infection had a relatively lower level of a urothelial bacteriostatic effect than did healthy controls.”

Another study will show that antimicrobial prophylaxis after surgery is subject to considerable variation. “The assumption that improved compliance would lead to reduced infectious complications needs to be tested,” he said.

Researchers from various institutions continue to address the challenging problem of infection following prostate biopsy.

“A number of abstracts confirm that post-prostate biopsy infection rates are related to inappropriate antimicrobial prophylaxis,” Dr. Schaeffer said, “and that targeted prophylaxis based on pre-biopsy cultures can lead to a significant reduction in infectious complications.”

Here are Dr. Schaeffer's abstract picks for the 2014 AUA annual meeting:

MP8-08: Urinary NGAL Deficiency in Children with Recurrent UTI
Catherine S. Forster

MP8-10: Perioperative Antibiotic Prophylaxis in Urologic Surgery: Assessment of Compliance with AUA Best Practice Guidelines
Matthew Mossanen

MP16-13: Rectal Swab Culture-Directed Antimicrobial Prophylaxis for Prostate Biopsy is Associated With A Lower Risk of Infectious Complications
Jessica Dai

MP16-14: Rectal Culture Prior to Prostate Biopsy Identifies Men At Risk For Infection: A Multi-Institutional International Collaborative Study
Michael Liss

MP16-15: Pre-biopsy screening of rectal flora for fluoroquinolone resistance: It's impact on sepsis after transrectal ultrasound guided prostate biopsy.
Michael Holmes

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