Positive surgical margins predict increased cancer recurrence

Chicago-Positive surgical margins are associated with an increased riskof cancer recurrence after radical prostatectomy, and adjuvant radiationtherapy given before recurrence may benefit patients with positive margins,according to a Memorial Sloan-Kettering Cancer Center study.

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January 16th 2025

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Hannah Clarke

In total, 40.3% of patients experienced a change in staging between initial assessment on conventional imaging and PSMA PET.

January 14th 2025

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Panelists discuss how managing overactive bladder in older adults requires a holistic approach that integrates treatment of comorbidities, emerging therapeutic options, and quality-of-life considerations to optimize patient outcomes.

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The NDA is supported by data from cohort 2 of the phase 2b SunRISe-1 trial.

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Wayne Kuang, MD Bilal Chughtai, MD

Experts discuss overactive bladder and the impacts on quality of life, distinguishing OAB from BPH, and how a delayed diagnosis can worsen symptoms.

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“In this phase 2 study, an image-guided adaptive strategy enabled radiotherapy dose escalation to over 86% of patients’ bladder tumors without significant increase in toxicity,” wrote the authors.

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