TCC missed in apparent interstitial cystitis patients

Today, many patients with apparent interstitial cystitis receive diagnosesbased on the minimally invasive (but not very specific) potassium sensitivitytest and the pelvic pain urgency/frequency (PUF) questionnaire-not throughcystoscopy and hydrodistension under anesthesia, which has been the goldstandard. That means that when the irritative voiding symptoms are in factcaused by transitional cell carcinoma of the bladder, they can be misdiagnosedas IC.