The AUA Clinically Localized Prostate Cancer guideline: FAQs for urologists

The American Urological Association (AUA)'s guideline on clinically localized prostate cancer was amended in 2026 to sharpen its recommendations on risk stratification, staging, and risk-based management, while incorporating new evidence on imaging and systemic therapy intensification for higher-risk disease.¹ The updates touch nearly every stage of the care pathway, from how patients are risk-stratified at diagnosis through how they are followed after treatment.