Hydrogel spacer may reduce rectal irradiation in patients receiving RT for prostate cancer

July 30, 2020

Injection of an absorbable perirectal hydrogel spacer prior to radiotherapy for prostate cancer may reduce rectal irradiation and the associated rectal toxic effects that manifest clinically after longer-term follow-up.

Darolutamide efficacy sustained in nonmetastatic CRPC patients with rapid PSA doubling time

July 30, 2020

A subgroup analysis of the pivotal phase 3 ARAMIS trial showed that the efficacy of darolutamide was sustained in patients with a rapid PSA double time.

Wearable neuromodulation device shows promise for overactive bladder

July 30, 2020

Feasibility study results indicate the nonimplanted, intravaginal device is safe and comfortable.

5-year data sustain water vapor thermal therapy benefit in BPH-related LUTS

July 30, 2020

Minimally invasive water vapor thermal therapy offers rapid improvements in LUTS, QoL, and flow rate that remain durable to 5 years in patients with lower urinary tract symptoms due to benign prostatic hyperplasia.

FDA grants novel HIF-2α inhibitor accelerated regulatory pathway in renal cell carcinoma

July 29, 2020

The novel HIF-2α inhibitor MK-6482 led to a decrease in the size of target lesions in almost 90% of patients with von Hippel-Lindau disease–associated renal cell carcinoma.

Thulium fiber laser shows efficiency advantage in experimental setting

July 29, 2020

Super-pulsed thulium fiber laser (TFL) has greater efficiency than a holmium:YAG laser, even when using the TFL with a smaller core-diameter fiber, according to preclinical findings.

Algorithm may predict health-related quality of life in patients with urolithiasis

July 28, 2020

The machine learning algorithm incorporates readily available clinical information.

Men on active surveillance for prostate cancer may benefit from Mediterranean diet

July 28, 2020

Mediterranean diet score was modestly associated with time to grade group progression.

Are phase 3 HERO results a game-changer for urologists?

July 28, 2020

"This new therapy could change the landscape for the treatment of advanced prostate cancer," Thrasher writes.

Study reveals risk factors for upgrading in active surveillance for prostate cancer

July 27, 2020

“Our findings suggest that genomic score and PSA density are risk factors for upgrading within 3 years of commencing active surveillance,” the investigators wrote.