
In the FIT-001 trial, the combination of darlifarnib and cabozantinib demonstrated promising early antitumor activity in patients with ccRCC who had previously progressed on cabozantinib.
Ayanambakkam is an assistant professor of hematology oncology and an adjunct assistant professor of urology, associate program director of the OUHSC Hematology Oncology Fellowship Program, medical director of the Genitourinary Medical Oncology Research & SCC Infusion Center at Stephenson Cancer Center, University of Oklahoma Health Sciences Center.

In the FIT-001 trial, the combination of darlifarnib and cabozantinib demonstrated promising early antitumor activity in patients with ccRCC who had previously progressed on cabozantinib.

Adanma Ayanambakkam, MD, MS, discusses the FIT-001 trial and early findings on the safety profile for darlifarnib plus cabozantinib in ccRCC.

Although the trial includes multiple tumor types, the presented data focus on RCC, predominantly clear cell disease.