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It is known that penile implants coated or impregnated with antibiotics produce lower short-term, post-surgical infection rates than implants not treated with antibiotics, but researchers from several institutions are now reporting lower infection rates over the long term, as well.

This list of U.S.-based National Institutes of Health trials is derived from the NIH's database and includes phase II, III, and IV erectile dysfunction trials that are currently recruiting participants. This list is current as of March 17, 2010.

A 2-year assessment of patients implanted with the urethral bulking agent Macroplastique (Uroplasty, Minnetonka, MN) for the treatment of female stress urinary incontinence showed that 84% of patients maintained significant improvement from their 12-month assessment.

Sipuleucel-T (Provenge) extends overall survival in men with metastatic, castrate-resistant prostate cancer, investigators in Dendreon Corp.?s phase III IMPACT (IMmunotherapy for Prostate AdenoCarcinoma Treatment) study recently announced at the 2010 Genitourinary Cancers Symposium in San Francisco.

Results from a phase III trial have shown that cabazitaxel, an investigational compound, plus prednisone/prednisolone significantly improved overall survival and progression-free survival in patients with metastatic hormone-refractory prostate cancer whose disease progressed following treatment with docetaxel (Taxotere)-based chemotherapy.