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Serum-based tumor markers are not used in more than half of all patients who have testis cancer, report researchers at the University of Michigan Comprehensive Cancer Center, Ann Arbor.

The FDA has approved SpermCheck Vasectomy (ContraVac, Inc., Charlottesville, VA), a diagnostic product that confirms men’s post-vasectomy sterility. The device will enable men to test their post-vasectomy fertility status at home, rather than returning to the physician’s office or a laboratory for confirmation.

PSA levels typically have correlated with prostate biopsy results in the detection of prostate cancer, but that correlation no longer exists for men with a normal prostate exam, suggest results of a study published online in Cancer. The study suggests that improved biopsy techniques make PSA less useful in prostate cancer screening.

Substantial variation in the prescribed and delivered doses of intensity-modulated radiation therapy for prostate and other cancers exists among medical institutions, raising concerns about the validity of comparing clinical outcomes, according to a University of Pennsylvania study published in the Journal of the National Cancer Institute (2008; 100:300-7).

The department of urology at Wake Forest University Baptist Medical Center, Winston-Salem, NC, has added three new urologic oncologists to its faculty: Ashok K. Hemal, MD, A. Karim Kader, MD, PhD, and Joseph A. Pettus IV, MD.

Ferring Pharmaceuticals has submitted applications in the United States and Europe for the marketing authorization of its prostate cancer treatment, degarelix, a new gonadotrophin-releasing hormone receptor blocker intended for patients in whom androgen deprivation is warranted.

An independent data monitoring committee stopped a major phase III clinical trial of the investigational drug everolimus (RAD001) after interim results showed significantly better progression-free survival in patients with advanced kidney cancer who received everolimus compared with placebo.

The FDA has approved an expanded clearance for the CellSearch System to be used as an aid in monitoring patients with metastatic prostate cancer. The system currently is cleared for monitoring metastatic breast and colorectal cancer patients.

A new blood test that measures levels of endoglin appears to accurately predict 98% of prostate cancers that will spread to regional lymph nodes, according to a study published in Clinical Cancer Research (2008; 14:1418-22). Endoglin is a plasma biomarker that has been previously shown to predict the spread of colon and breast cancer.

The Medicare Payment Advisory Commission is expected to recommend to Congress this month that it increase average Medicare physician fees by 1.1% for 2009, rather than allowing a scheduled 5% reduction to take effect.

Poor communication skills are a frequently cited factor in a patient's decision to leave a practice or even pursue a malpractice claim against a physician.

It is incredibly tempting for readers to immediately look at the results of a study and determine the conclusions; however, the evidence-based mindset requires a more rational approach that questions the validity of the results, followed by a close inspection of them.