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Dr. Morgan discusses guideline for salvage therapy in prostate cancer

Opinion
Video

"There have been some pivotal clinical trials that have reported out, and they've really showed us that there is limited to maybe no role for adjuvant treatment after prostatectomy, and there is a huge role for early salvage treatment," says Todd M. Morgan, MD.

In this video, Todd M. Morgan, MD, discusses the background behind the AUA/ASTRO/SUO guideline for salvage therapy for prostate cancer, which was recently published in the Journal of Urology. Morgan is chief of urologic oncology, the Jack Lapides M.D. Research Professor and professor of urology at the University of Michigan, Ann Arbor.

Transcription:

Please describe the background for this guideline.

There was another guideline previously, and it was the 2013 AUA and ASTRO guideline on adjuvant and salvage therapy, particularly radiation after surgery. What's happened over the last 10 years is just that the field has shifted. There have been some pivotal clinical trials that have reported out, and they've really showed us that there is limited to maybe no role for adjuvant treatment after prostatectomy, and there is a huge role for early salvage treatment. We know this from just a ton of data. We also know that salvage treatment after surgery in particular, but also after radiation is underutilized. And really early salvage therapy is underutilized, and that means providing salvage treatments when the PSA has shown us that there's a recurrence but isn't particularly high. And so there's this window for cure. And that window for cure is really in a sweet spot that is underutilized, and a huge impetus for the guidelines is to address that problem and really disseminate that information that there's an appropriate time to consider salvage therapy and we need to jump on that because these are chances for cure.

This transcription was edited for clarity.

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