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Management of men with Peyronie disease and erectile dysfunction

Key Takeaways

  • Treatment focus depends on whether erectile dysfunction or penile curvature is the primary concern for the patient.
  • Severe erectile dysfunction often leads to the recommendation of a penile prosthesis, addressing both conditions simultaneously.
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"It's often a balancing act of truly kind of pinning down people on what exactly they want to treat," says Landon Trost, MD.

In this video from the 2024 Sexual Medicine Society of North America Fall Scientific Meeting, Landon Trost, MD, discusses the treatment of patients with both Peyronie disease and erectile dysfunction. Trost is the founder and director of the Male Fertility and Peyronie’s Clinic in Orem, Utah.

Transcription:

Peyronie disease often coexists with erectile dysfunction. How do you approach the management of both conditions simultaneously? Are there specific therapeutic strategies that can address both issues effectively?

It's often a balancing act of truly kind of pinning down people on what exactly they want to treat. If someone's coming in and erectile dysfunction is their primary complaint, then you're going to focus much more heavily on more heavily on that, compared to if it's really the curvature or the indent or length loss, or what it is that they're interested in. When someone does have more severe erectile dysfunction, it's an easy answer. You put in a penile prosthesis, and that addresses both conditions. If someone, though, has mild erectile dysfunction, which is much more common with men who will come in with Peyronie disease, then you have to balance it a little bit more as far as outcomes. If you get a 70-year-old with what they call mild erectile dysfunction, you just know in the back of your head, pretty much any therapy I do may push them over to the point where they need a prosthesis. Whereas you get a 50-year-old with the same complaint, they're going to be much more resilient against any therapies, whether it's Xiaflex or surgery or whatever the case. So really, you do factor in multiple things in trying to decide, and really, the most important is just notifying the patient of best case, worst case, and most likely outcome, and then helping them to make a decision as to what they want to do.

This transcript was AI generated and edited by human editors for clarity.

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