• Benign Prostatic Hyperplasia
  • Hormone Therapy
  • Genomic Testing
  • Next-Generation Imaging
  • UTUC
  • OAB and Incontinence
  • Genitourinary Cancers
  • Kidney Cancer
  • Men's Health
  • Pediatrics
  • Female Urology
  • Sexual Dysfunction
  • Kidney Stones
  • Urologic Surgery
  • Bladder Cancer
  • Benign Conditions
  • Prostate Cancer

Molecular Mechanisms in Prostatic Carcinogenesis

Article

In the developed world, environmental factors-particularly diet-seem to play a prominent role in the development of prostate cancer.27 Research into the molecular pathogenesis of prostate cancer may help us assess why prostate cells are particularly vulnerable to such environmental effects and to determine what somatic genome mutations are involved in the transformation of normal epithelium into intraepithelial neoplasia (PIN) and ultimately to invasive carcinoma (Figure 5).

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