Peyronie's disease resulting in shorter and curved erections occurs more commonly than the 1% to 2% of the population related in textbooks. Patients with the problem may be embarrassed to come forward, or the angulation of the erection-although uncomfortable-may not prohibit intercourse. But with more open discussion of sexuality in all forms of the media, more men are coming forward for treatment of sexual problems. Past medical treatments have been unsuccessful in restoring a straight erection in such patients. Reports of newer treatments such as intralesional verapamil and collagenase have been inconsistent and must stand the test of time.
Engy Habashy, MD, discusses key takeaways from the 2025 AUA GSM guideline, including the role of androgens and hormonal therapies in managing genitourinary syndrome of menopause.
Chad R. Ritch, MD, MBA, FACS, discusses how PSMA-PET informs staging, treatment planning, recurrence workup, and the interpretation of equivocal findings.
Michael S. Cookson, MD, MMHC, FACS, discusses how Anktiva’s expanded FDA approval may broaden bladder-preserving treatment options for BCG-unresponsive papillary-only NMIBC.
The investigational HIF-2α inhibitor casdatifan demonstrated antitumor activity as monotherapy and in combination regimens across the ARC-20 platform study.