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The Importance of Serum Testosterone Levels With the Use of Androgen Receptor-Targeting Therapies

Panelists discuss how the STAAR study (Stein, 2018) indicates that the micronized abiraterone formulation results in lower average serum testosterone levels in 25% of patients compared to 17% with the originator formulation, potentially influencing treatment selection.

  • To what extent do average serum testosterone levels guide selection between abiraterone formulations?
  • STAAR study: Average serum testosterone levels≤0.1 ng/dL occurred in 25% of patients treated with micronized formulation vs 17% of patients receiving the originator formulation.

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