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OnabotulinumtoxinA (Botox) has earned FDA approval for the treatment of overactive bladder in adults who cannot use or don't adequately respond to anticholinergic drugs, and its potential uses in urology may not end there.

Publication of the Value of Urodynamic Evaluation study has drawn attention to whether urodynamics improves patient outcomes when added to an office evaluation of stress urinary incontinence before surgical intervention.

Drugs and devices in the pipeline from Bayer Healthcare, AVEO Oncology, Astellas Pharma Inc., Trimel Pharmaceuticals Corp., OncoGenex Pharmaceuticals, Inc., Nymox Pharmaceutical Corp., Spectrum Pharmaceuticals, and Tengion, Inc.

Recent analyses of urodynamic testing data indicate that both autologous fascial pubovaginal sling and synthetic midurethral sling procedures decrease maximum flow rate and increase bladder outlet resistance, but the pubovaginal sling was found to create more bladder outlet resistance.

One in five U.S. physicians are over 65 years of age as of 2010, the American Medical Association reports. Some experts say that regular cognitive and physical screenings are needed once physicians reach 65 or 70 years of age, but no standardized screening is available. Age, of course, is not always a negative factor, says urologist Sivaprasad D. Madduri, MD.

Many synthetic chemicals, untested for their disrupting effects on the hormone system, may have significant health implications, including contributing to the development of prostate cancer in men and undescended testes in young males.

Three "field effect" epigenetic biomarkers were found to be more prevalent in histologically benign biopsy cores from prostate cancer patients diagnosed with Gleason score 7 prostate cancer than in those with low-volume Gleason 6 disease, researchers reported at the Genitourinary Cancers Symposium in Orlando, FL.

A large study presented at the Genitourinary Cancers Symposium in Orlando, FL has confirmed that prostate cancer detection rates are enhanced when 10 to 12 specimens are obtained during biopsy.

Women who have unsuccessful midurethral sling surgery for stress urinary incontinence and then undergo a second midurethral sling surgery see more quality of life symptom improvement than women who undergo only a first procedure, a new study from the University of Alabama at Birmingham found.

The FDA has granted priority review to the new drug application filed for radium-223 dichloride, an investigational compound under review for the treatment of patients with castration-resistant prostate cancer who have bone metastases.

A large retrospective study of older patients diagnosed with small kidney tumors showed that patients who undergo surgery to remove these tumors have the same risk of dying of kidney cancer over a 5-year period as those who undergo surveillance.

Like all physicians, urologists face multiple challenges in 2013. As part of its seventh State of the Specialty survey, Urology Times asked practicing urologists a number of questions about their career satisfaction. The results may surprise you.

New data suggest the phosphodiesterase type-5 inhibitor tadalafil (Cialis) may be beneficial in helping men who have problems with ejaculation and orgasm, report researchers from New York-Presbyterian Hospital/Weill Cornell Medical Center, New York.