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While Agent Orange, an herbicide used during the Vietnam War, has been previously linked to a variety of types of cancers in Vietnam veterans, new data from the Veterans Affairs Medical Center in Shreveport, LA, indicates that there may be a connection between veterans? in-country exposure and subsequent development of renal cancer.

Results of a retrospective study investigating men with clinically localized prostate cancer who underwent radical retropubic prostatectomy with bilateral pelvic lymph node dissection (PLND) show a higher than expected incidence of LN metastases, but men with nodal involvement had excellent 10-year clinical recurrence-free survival.

Among men receiving early androgen deprivation therapy (ADT) for biochemical recurrence after radical prostatectomy, obesity appears to be a significant risk factor for poorer prognosis, according to the results of a retrospective study presented yesterday.

A population-based study evaluating 25-year trends in renal stone findings among children reported a 4% per year increase in incidence, driven largely by consistently escalating renal stone rates in the 12- to 17-year age group, Mayo Clinic researchers reported yesterday.

Urologists attending localized prostate cancer sessions at the upcoming AUA annual meeting in Washington will hear more about the ongoing debate on open versus minimally invasive radical prostatectomy, the use of 5-alpha-reductase inhibitors (5-ARIs) in men on active surveillance, and updates on treatment approaches such as high-intensity focused ultrasound.

In the area of urologic infections and inflammation, research to be presented at this year's AUA annual meeting in Washington will highlight an ongoing trend toward understanding and attempting to modify the human microbiologic environment for patients' benefit.

Of the many questions raised by the advent of robot-assisted surgery, two are germane to robotic sacrocolpopexy: Does the technology increase the risk of stress urinary incontinence in women undergoing the robotic procedure, and if it does, should an anti-incontinence procedure accompany the primary procedure as prophylaxis against incontinence?

This list of U.S.-based National Institutes of Health trials is derived from the NIH's database and includes U.S. phase I and II localized prostate cancer trials that are currently recruiting participants as well as phase IV U.S. incontinence/overactive bladder trials. This list is current as of April 22, 2011. more information, view the complete database at http://ClinicalTrials.gov.

Research investigating the ability to detect low levels of circulating tumor cells and to correlate their quantity with clinicopathologic parameters in men with advanced prostate cancer who have undergone surgery or radiotherapy is still at an early stage, but the initial results suggest this method has promising prognostic value.

The newest urology products and services from IPC Medical Corp., Mission Pharmacal, Microline Surgical, Inc., the American Medical Group Association, Uramix, Inc., WellComm, and Graceway Pharmaceuticals, Inc.

Urology drugs and devices that are in the pipeline from immatics biotechnologies GmbH, Neotract Inc., Abbott Laboratories, and Beech Tree Labs, Inc.