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Researchers have identified a four-gene signature that may significantly advance the current clinical ability to differentiate indolent from aggressive prostate cancer in the mouse model and in human tissue samples.

Men who regularly use nonsteroidal anti-inflammatory drugs (NSAIDs) have an increased risk of erectile dysfunction.

Surgeons who care for men with Peyronie's disease must be familiar with grafting procedures in order to offer the full spectrum of options.

Results from in vitro and preclinical models provide proof of concept that SPINK1 (serine peptidase inhibitor, Kazal type 1) may be a viable therapeutic target for a subset of prostate cancer patients with an aggressive subtype of disease.

Evidence of MSH5 mismatch repair gene deficiencies in nonobstructive azoospermic men suggests that these men should receive genetic counseling if they plan to have children via intracytoplasmic sperm injection.

Sperm retrieval rates for microdissection testicular sperm extraction remained constant between 1997 and 2009, except for an increase in SRRs in patients with Sertoli cell only.

In adults receiving radiotherapy for cancer, a relatively small proportion of second cancers are related to the treatment itself, suggesting that most are due to other factors, such as lifestyle or genetics, according to a recent study.

Mutations of a gene called KRAS may drive metastatic prostate cancer, say researchers from the University of Michigan, Ann Arbor.

A new PSA test appears to more accurately identify men with prostate cancer, particularly the aggressive form of the disease, and substantially reduce false positives compared with the two currently available tests, say researchers from Northwestern University, Chicago.

The American Board of Medical Specialties (ABMS) has announced the creation of physician certification in female pelvic medicine and reconstructive surgery, which will be administered by the American Board of Obstetrics and Gynecology (ABOG) and the American Board of Urology (ABU).

Two novel genetic markers appear to be associated with earlier time to prostate cancer diagnosis among African-American men, according to research presented at the American Association for Cancer Research annual meeting in Orlando, FL.

Uroplasty, Inc., has announced that several payers will cover posterior tibial nerve stimulation (PTNS) using the company's Urgent PC Neuromodulation System for the treatment of overactive bladder and associated symptoms.

Rather than looking for tumors directly in patients with prostate cancer, analyzing non-tumor tissue may be an effective option as well, according to a recent study.

Genetic factors explain half of a person?s susceptibility to urinary incontinence, Swedish researchers report.

Parkinson's disease appears to be associated with an increased risk of prostate cancer, and this increased risk also extends to close and distant relatives of individuals with Parkinson's disease, according to research presented at the American Academy of Neurology annual meeting in Honolulu.

Central Texas-based St. David?s HealthCare has announced the establishment of Texas Institute for Robotic Surgery at St. David?s North Austin Medical Center, which has recruited urologist Randy Fagin, MD, as the institute?s chief administrative officer.

Prostatic artery embolization appears to show comparable clinical results to transurethral resection of the prostate without the associated risks, according to research presented at the Society of Interventional Radiology annual scientific meeting in Chicago.

Combining radiotherapy with 6 months of androgen deprivation therapy doubles the survival chances of men with locally advanced prostate cancer, according to Australian researchers.

A new study on the use of PSA-based prostate cancer screening in the United States has found that many elderly men may be undergoing unnecessary prostate cancer screenings. At the same time, a significant percentage in their fifties are not being screened.

Using the pelvic organ prolapse quantification exam, the Elevate Anterior and Apical Prolapse Repair System (American Medical Systems, Minnetonka, MD) has demonstrated 6-month efficacy rates of stage 1 or less to be 86.3% for anterior and 98.8% for apical prolapse, according to findings from a prospective, multicenter study.

Robot-assisted radical prostatectomy is safe over the long term, with a major complication rate of less than 1%, say researchers at Henry Ford Hospital?s Vattikuti Urology Institute, Detroit.

GlaxoSmithKline has announced that it will no longer pursue global approval for the use of the 5-alpha-reductase inhibitor dutasteride (Avodart) to reduce the risk of prostate cancer.

Nearly three-fourths of men who receive androgen deprivation therapy post-radical prostatectomy gain significant weight in the first year, putting on an average of 4.2 kg, according to a recent study.

When clinicians engage men in discussions of treatment for prostate cancer, they should keep in mind the very real impact of obesity on the man's overall prognosis - a risk that for some men may be more significant than that presented by the malignancy.

Cauterizing Hunner's lesions can give huge relief to patients who have them. But there may be another way to get results that may be just as good with somewhat fewer risks-cystoscopic injection of the lesions with the steroid triamcinolone.

Pelvic lymph node dissection in patients undergoing robot-assisted laparoscopic prostatectomy is feasible, adds little time or morbidity to the procedure, and may provide important prognostic data.

While many older physicians retain excellent clinical skills into their seventh decade and beyond, questions have been raised about age-related illness in older clinicians and how it affects their ability to practice.