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Urology Times has announced the expansion of its editorial content in 2008. Beginning in March, the publication’s content mix will be expanded to include practical, peer-reviewed clinical articles in a quarterly supplement known as Urology Times Clinical Edition. This addition will complement the publication’s current offerings: news from major meetings, Q&A interviews with urology’s thought leaders, analysis of legislation affecting urologists, and valuable practice management information.

Fox Chase Cancer Center, Philadelphia, has named urologist Robert G. Uzzo, MD, vice chairman of the department of surgical oncology. Nationally known as a leader in the field of urologic oncology, Dr. Uzzo has made important clinical, scientific, and educational contributions to the department. In addition, Dr. Uzzo became acting chairman of the department on Jan. 1.

Indevus Pharmaceuticals, Inc. has received a non-approvable letter from FDA for valrubicin for intravesical instillation (Valstar), related to the drug’s chemistry, manufacturing, and controls new drug application supplement submitted to the FDA last May. Valrubicin is indicated for bacillus Calmette-Guerin-refractory carcinoma in situ of the bladder in patients for whom immediate cystectomy would be associated with unacceptable morbidity or mortality.

Bayer HealthCare Pharmaceuticals, Inc. said it will discontinue marketing of leuprolide acetate implant (Viadur), which is indicated for the treatment of advanced prostate cancer. Based on diminished market demand and growing manufacturing costs, the company has concluded that the product has limited long-term market viability. Bayer said the decision is not the result of safety or efficacy issues.

Just 4 months of hormonal therapy before and with standard external beam radiation therapy slows cancer growth by as much as 8 years-especially the development of bone metastases-and increases survival in older men with potentially aggressive prostate cancer, according to a study to be published in the Journal of Clinical Oncology.

Baby aspirin appeared to interfere with the ability to deliver a full course of hormone therapy in 206 men with localized but high- or intermediate-risk prostate cancers who were enrolled in a study comparing radiation therapy alone with radiation therapy plus hormone therapy. In a letter to the editor of the New England Journal of Medicine (2007; 357:2737-8), Anthony V. D’Amico, MD, PhD, and Philip W. Kantoff, MD, of the Dana–Farber Cancer Institute, Boston, discussed the effects of low-dose aspirin on liver function tests.

Older men with low testosterone levels who received testosterone supplementation increased lean body mass and decreased body fat, but were no stronger and had no improvement in mobility or cognition compared with men who did not use the supplement, according to a study published in JAMA (2008; 299:39-52).

The combination of bevacizumab (Avastin) and interferon-alpha (Roferon-A) as first-line treatment in patients with metastatic renal cell carcinoma offers significant improvement in progression-free survival compared with interferon-alpha alone, according to a study published in The Lancet (2007; 370:2103-11).

In the closing days of the 2007 session, Congress prevented a Medicare payment cut and kept the State Children’s Health Insurance Program (SCHIP) alive, but both moves are only temporary. By unanimous consent on Dec. 18, 2007, the Senate passed the Medicare, Medicaid and SCHIP Extension Act of 2007. The House passed the same legislation 411-3 the next day, and President Bush signed the measure into law on Dec. 29.

Bathe a prostate tumor in metallic particles that preferentially move through permeable capillaries and into the tumor bed. Shine an infrared light on the particles. The metal, but not the tissue, absorbs infrared energy; as it heats, it destroys tumor cells. Tissue not in contact with the metal particles, ie, healthy tissue, is unaffected.

The pace of prostate growth in a majority of men of northern European descent is as steady as a ticking clock and gives clinicians the opportunity to forecast prostate size in many patients with a single ultrasound measurement.

The pace of prostate growth in a majority of men of northern European descent is as steady as a ticking clock and gives clinicians the opportunity to forecast prostate size in many patients with a single ultrasound measurement.

Although there is no confirmed direct link between testosterone replacement therapy and prostate cancer, a recent study suggests that physicians treating middle-aged hypogonadal men with extrinsic testosterone should be more vigilant in monitoring these patients' PSA levels than they would be in monitoring average men of the same age.

Once again, urologists are at the mercy of the politicians in Washington with a 10.1% average payment rate cut scheduled to take effect this month unless some way, somehow Congress once again comes to the rescue-and President Bush signs whatever legislation is passed.

The specialty of urology is evolving dynamically. With changes in techniques and treatment protocols have come significant practice challenges, including a declining work force, an increased focus on procedures, and competition from other specialties.

Members of the American Association of Ambulatory Surgery Centers (AAASC) and Foundation for Ambulatory Surgery in America (FASA), the nation’s largest ASC associations, voted nearly unanimously to approve the proposed merger of the groups. Effective Jan. 1, 2008, the two organizations will become one, known as the Ambulatory Surgery Center Association, or ASC Association.

Mission Pharmacal has sold the rights to its line of kidney stone diagnostics to Quest Diagnostics Inc. Products in the diagnostic line include UroRisk Diagnostic Profile, StoneRisk Diagnostic Profile, StoneTrack Diagnostic Monitoring Test, StoneRisk Citrate Test, and StoneRisk Cystine Tests. These tests are designed to help physicians diagnose patients who are symptomatic and, among those who previously had a stone, help in periodic evaluations of a patient’s propensity to form stones.