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Atlanta-The decision about when to intervene in patients with small, low-grade prostate tumors can be a tough one for both patient and physician. A study from The Johns Hopkins Hospital, Baltimore, suggests that these men may have 2 years or longer to make a decision without compromising effective treatment.

Atlanta-Laurence H. Klotz, MD, looks momentarily at the data generated by his study of the role that PSA kinetics might play in influencing intervention in men with low-risk prostate cancer and summarizes the findings in a single observation: "It is hard to argue with 99% disease-specific survival."

Atlanta-Phosphodiesterase-5 inhibitor therapy, which is commonly used to treat erectile dysfunction, may have a paradoxical benefit as a treatment for priapism in patients with sickle cell anemia, according to research presented at the AUA annual meeting here and at the American Society of Andrology annual meeting in Chicago.

Atlanta-Which procedure nets better results for patients with Peyronie's disease-corporeal plication or plaque incision with venous grafting? According to a long-term study from Kaiser Permanente Medical Center in Los Angeles, there is no difference between the two procedures in terms of patient satisfaction. The major difference between the two is time spent in the operating room.

Atlanta-Surgeons from Italy have developed a technique to take tissue from the underside of the tongue and transplant it to repair strictures in the urethra, giving surgeons an alternative to buccal mucosa for the procedure.

Atlanta-Remission of erectile dysfunction may be more common than has been previously believed, according to an analysis of data from the National Institutes of Health-supported Massachusetts Male Aging Study (MMAS). Findings from this analysis were reported at the AUA annual meeting here.

Atlanta-Testosterone replacement therapy (TRT) caused no adverse events in the prostate tissue of men with androgen decline of aging male (ADAM) syndrome after 6 months of treatment, according to a study presented at the AUA annual meeting here.

The University of Texas M.D. Anderson Cancer Center, Houston, has started treating patients at its Proton Therapy Center, the first facility associated with a comprehensive cancer center and the fourth such facility in the United States.

An external or "condom" catheter appears to reduce the risk of urinary tract infections or death by 80 percent compared with an indwelling catheter, according to a randomized, controlled trial comparing the two types of catheters.

The second of two phase III trials has shown that once-daily trospium chloride (Sanctura XR) reduces frequency of urination and the number of urge incontinence episodes in individuals with a once-daily formulation for the treatment of overactive bladder.

Men who receive radiation therapy for prostate cancer are not at any appreciable increased risk of developing rectal cancer compared with those not given radiation therapy, according to a recently published study by Canadian researchers.

A new prognostic test may help determine whether a patient with prostate cancer will have a recurrence of the disease, even if surrounding lymph nodes initially appear negative for cancer, according to a study from the Keck School of Medicine at the University of Southern California, Los Angeles.

Moderately and severely obese prostate cancer patients had a 99% greater risk of developing biochemical failure than other patients, according to the authors of a study from the University of Texas M.D. Anderson Cancer Center, Houston.

After finding the lumen of a needle guide of an ultrasound transducer assembly soiled during patient safety rounds at a VA hospital, the FDA has issued a public health notification about the importance of properly cleaning and sterilizing reusable ultrasound biopsy transducer assemblies and guidelines for doing so.

Administration of sipuleucel-T (Provenge) in men with advanced androgen-independent prostate cancer shows a significant survival benefit and "a very favorable toxicity and safety profile," according to the authors of a double-blind, placebo-controlled, multicenter phase III study published recently in the Journal of Clinical Oncology (2006; 24:3089-94).

Atlanta-Intraprostatic injection of botulinum toxin A (Botox) is a safe and effective treatment in patients with symptomatic BPH that results in improvements in symptoms and quality of life that may persist for up to 1 year, Chinese researchers reported at the AUA annual meeting here.

A urologist from another practice mentioned that his practice has made some changes in its retirement plan to create greater benefits for the doctors. He thought the new plan was called a "cash balance plan." Does this really work?

Many urologists are in the process of trying to transition their practices from the hospital to the office, and are looking for opportunities for ancillary income. A number of ancillary services are being explored.