Since its inception in 1995, the Cancer of the Prostate Urologic Research Endeavor has become one of the world's largest databases on prostate cancer. CaPSURE shows a rapidly evolving picture of how the disease is treated and the typical patient confronting it. In this exclusive Urology Times interview, Peter R. Carroll, MD, CaPSURE's principal investigator, discusses these trends and the forces driving them. The interview was conducted by UT Editorial Consultant Richard D. Williams, MD, professor and chairman of the department of urology, University of Iowa, Iowa City.